The Cosy Club, part of the Loungers business, has taken space on the ground and first floor of the property and created 35 jobs.
Legal firm Sampson Coward has also relocated to the property from its current office at St Thomas’s Square. The business, which has 15 members of staff, has taken part of the ground, first and second floors of the building.
Both businesses have taken space on a 15 year lease, with rental terms not disclosed. The deals were completed through regional commercial property consultancy Myddelton & Major.
Dean Speer, a partner at Salisbury-based Myddelton & Major, said: “The occupancies are great news for the city, generating jobs, inward investment and generally adding to the vitality of the business district and the city centre in general.
“College Chambers will be a familiar building to many people and their families through the generations. It was originally Hamilton Hall, a literary and scientific institution, and, many decades later, the City of Salisbury School of Arts & Crafts until the property was converted into offices after the 1960s.
“College Chambers had been vacant for four years following the global credit crunch in 2008 but now has a new lease of life.”
College Chambers dates back to 1870 and the property comprises of 8,677 sq ft of space.